There’s a new release at Kelly Purkey Shop today and I wanted to share the two projects I made with this month’s release. The stamps and kits are all about summer fun and I was happy to work with them since we’ve been experiencing “June Gloom” here in southern California.
For my first project, I used the main TN kit called Summer Bucket List to document a week last year checking off the items on my bucket list. We spend a lot of time at the beach and at the pool – both as a family and solo for me, since I am avid swimmer. Many of the photos from the week were taken at both locations and I think I made at least 6 trips to the pool and beach that week. 🙂
When I first saw the TN papers, I was drawn to the large “Here Comes Summer” page. I cut down that page to use in a 4″ x 6″ pocket (layered over some white cardstock) and adhered a small photo of my daughter in the pool.
Since I was documenting my summer bucket list, I had to use the stamps from the kit to make a journaling card, with the completion dates. I used white embossing powder to make “summer bucket list” stand out on the dark blue paper.
I loved the circle patterns on the papers and stamped some of the sentiments over the circles and cut them out using a circle punch to use as embellishments on other photos.
Lastly, I cut out phrases from the fill-in-the-blank TN page to further embellish my photos. A few puffy asterisks from my stash completed the spread!
For my second project, I documented a recent week this year where I thought summer was starting to show up. Spoiler: Summer was just teasing me because it was sunny that week and then it was back to clouds the following week!
For this spread, I mixed cards from the main project kit, Fun Times, with the LLP kit, Summer Adventuring. We visited the beach twice that week and had fun collecting shells so the gorgeous Seashells stamp set by Life Love Paper was perfect to use. I loved playing with the different shells on my title page!
We also acquired a bike for my daughter which was exciting so the 3″ x 4″ card and matching sentiments from the Summer Adventuring kit was perfect for documenting that.
I used one of the journaling cards from the Fun Times kit to type some notes about things that happened during the week. The Sun’s Out stamp from Life Love Paper was great for adding an embellishment to the otherwise plain card. I popped it up with some foam tape.
A few more stamps and labels and my week was done! Thanks for checking out my projects and let me know if you have any questions!
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This is further supported by the existence of aromatase and estrogen receptors (ERs) throughout the rat and human penis [Jesmin et al., 2002; Dietrich et al., 2004] The straight excitement of GC to enhance cGMP levels separately of NO degrees has likewise been explored to cause cavernous smooth muscle relaxation utilizing soluble GC stimulators/activators, which bind to a website of the GC molecule independently of NO [62,63,64] Although a few of these compounds generate leisure of spacious smooth muscle mass and generate penile erection in vivo by enhancing cGMP degrees [36], when given systemically, these medications additionally caused a significant reduction in blood pressure and hindered platelet gathering [75] It seems unlikely then that these types of medicines, when offered systemically, could be used for the treatment of ED unless pro-erectile GC stimulators/activators not able to lower high blood pressure are found. Synchronised to the architectural optimization of discerning GLP1R and GIPR mono-agonists has actually been research to pharmacologically harness the reality that mammalian microorganisms govern power balance through much more than a single hormone. The most remarkable development in that instructions has been the exploration of poly-agonists that all at once target the GLP1, GIP and/or glucagon receptors188,189.
Also, endothelin-induced tightenings of the bunny and human corpus cavernosum are lowered in Ca2+- free service, or after therapy with nimodipoine (Ca2+ channel blocker) [Holmquist et al., 1990] This shows that ET-1 signalling partly counts on Ca2+ influx to drive smooth muscle contraction. Additionally, treatment of the rabbit corpus cavernosum with H7 (PKC inhibitor) lowers ET-1-mediated contraction artificial insemination and eliminates it in Ca2+- cost-free option [Holmquist et al., 1990] These outcomes provide evidence that ET-1 drives smooth muscle contraction in the penis by boosting intracellular Ca2+ degrees and enhancing Ca2+ level of sensitivity using PKC activation (Fig. 7). The NO-cGMP pathway reduces cytosolic Ca2+ and hinders the RhoA/Rho-kinase path as shown in Figure 4.
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PT-141, likewise called bremelanotide, binds to melanocortin receptors in the brain and sets off a waterfall of occasions that activate neural paths involved in sex-related stimulation. This activation impacts the launch of hormones like dopamine and oxytocin, in addition to the degrees of stress and anxiety hormones such as cortisol. As a result, PT-141 has actually shown encouraging results in dealing with sexual desire problems triggered by inequalities in neurotransmitters and hormonal agents. At the helm old Well MD, Dr. Rouzbeh Sattari, a distinguished medical professional and cum laude graduate from the University of Brussels, is redefining age management medicine with over twenty years of experience.
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